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Mesothelioma and Non Asbestos Exposure The majority of the time, mesothelioma is found on the lung linings as well as the abdomen. The rare cancer may also form in the linings of the heart or testes (pericardium). Asbestos exposure is the main risk factor for mesothelioma. However, some patients diagnosed with mesothelioma may not have an asbestos-related history. Exposure to Asbestos Asbestos, which is a mineral of natural origin, was previously used for construction and industrial products throughout the world. Workers in asbestos-related industries were exposed to asbestos every day. Asbestos fibers can get into the lungs, causing progressive lung disease. This is referred to as asbestosis. Over time the trapped fibers may cause mesothelioma. Asbestos can also be breathed in or ingested and the risk of mesothelioma and other asbestos-related diseases increases with the length and quantity of exposure. Most cases of mesothelioma stem from exposure to occupational toxins. Asbestos was used in various trades, such as construction, insulation and electrical work, as well as automobile maintenance and pipefitting. These professions are usually predominantly male-dominated and as a consequence mesothelioma-related cases of males comprise 75-80% of all reported cases. The gradual elimination of asbestos in the United States, and other first-world nations, has reduced occupational contamination. This has caused an increase in cases with occupational exposure becoming more common. Non-occupational mesothelioma can occur when asbestos is released from the workplace environment or is found in the school or home environment. Secondhand exposure can also cause it, such as when a family members touches the clothes worn by an asbestos worker. The people who suffer from this type of exposure may experience symptoms such as shortness of breath or chest pain, which is often mistaken as lung or heart problems. Certain studies have found a link between non-occupational exposure and mesothelioma, but the results aren't consistent. A majority of these studies were conducted with a small sample size, and between-study heterogeneity has been high. It is essential to conduct more studies to confirm the link between non-occupational asbestos exposure and mesothelioma. People who have been exposed to non-occupational asbestos should discuss their asbestos history with their physician. If they are concerned, they should seek for mesothelioma screening and a referral to a specialist. Specialists in mesothelioma can offer the most effective treatment and treatment to improve a patient's outlook. They will analyze medical records and conduct imaging tests to identify mesothelioma. They will also give guidance on how to file mesothelioma lawsuits to receive compensation from an asbestos trust fund. Secondhand Exposure While asbestos exposure is the primary cause of mesothelioma not the only reason to develop this cancer. In fact, there's a small amount of evidence that shows that people can develop mesothelioma despite not having directly handled asbestos or worked in an industry with asbestos-related activities. This is referred to as secondary or non-occupational exposure to asbestos. Asbestos fibers are extremely small and can adhere to hair, clothing skin, and other surfaces. Workers can carry harmful fibers in their work clothes home and transmit them to family members. These asbestos fibers can cause mesothelioma if inhaled or ingestion. This form of mesothelioma is more common in women, and usually occurs in the lungs. It can also affect the chest wall or abdomen. Shortness of breath is the most common sign. It may be caused by a variety of other symptoms, including lung fluid and swelling in the scrotum. The mesothelioma that occurs in the lungs is called mesothelioma pleural. Peritoneal mesothelioma refers to the name for mesothelioma, which affects the stomach wall or chest wall. This kind of mesothelioma could cause a number of symptoms including abdominal pain, difficulty breathing and constipation. A number of studies have shown that even those who have no prior background of occupational exposure to asbestos could develop mesothelioma due to exposure to asbestos through secondhand fibers. In most cases, they have been living with someone who was exposed to the hazardous substance. They could have handled the garments of the worker or had other contact with asbestos. Veterans are at a high risk of developing mesothelioma due to the extensive asbestos used in military bases, ships and other vehicles. The Navy is at a greater risk, as asbestos was used in the hulls and gun turrets of ships to protect them from fire. Asbestos was also brought home by sailors who had returned from their jobs aboard ships that had been affected by asbestos. Environmental Exposure A variety of substances have been linked to mesothelioma. However, the disease is most often associated with exposure to asbestos. Asbestos, a naturally occurring mineral was used in the manufacturing process for a number of years. The mineral is heat-resistant and durable, making it ideal for use in insulation, brakes, shingles flooring, and many other products. Asbestos is broken down to dust that can be inhaled and swallowed. These fibers can remain in the lungs or stomach for years, triggering mesothelioma symptoms. The most common symptoms of mesothelioma include chest pain as well as abdominal discomfort, and difficulty breathing. Asbestos sufferers might experience these symptoms for 20 to 60 years or more after their first exposure. The symptoms can be misinterpreted as other illnesses, so it is important to see your doctor if you exhibit these symptoms. It is also important to inform your doctor about your history with asbestos. This can help avoid a false diagnosis and ensure that you receive the proper treatment. Mesothelioma that is caused by exposure to asbestos is most frequent in those who have worked directly with asbestos, but it can also affect the loved relatives of those who have been exposed. This is referred to as secondary exposure. Family members may inhale or ingest asbestos fibers from a worker's shoes, clothing, or tools. They could be sprayed on the home by someone who is wearing or having hair. This is the reason that mesothelioma sufferers and their families must wash their clothes in a clean manner after working with asbestos. There is a huge collection of research demonstrating an association between nonasbestos and mesothelioma. However, there are still downey asbestos lawyer about the role of other agents. There is evidence to suggest that chlorosotile and erionite zeolites which can cause mesothelioma. Erionite is found in soil and rocks from certain areas in Turkey where the risk of mesothelioma pleural is high. The research on the connection between mesothelioma and nonasbestos exposure is continuing. Funnel plots have indicated the potential for publication bias, and between-study heterogeneity is very high. It is clear that asbestos exposure is the biggest mesothelioma-related risk factor. Genetics Mesothelioma is an uncommon disease caused by malignant mesothelial cells that grow out of control and invade surrounding tissues. It can be expand throughout the body through traversing the bloodstream or lymphatic system and impacting other organs. Asbestos is the most common cause, but it's not the only cause. The condition can also be triggered by other genetic or environmental factors. In a few cases, mesothelioma has occurred in people who were not exposed to asbestos. They are known as non-occupational mesothelioma patients. These individuals typically had indirect exposure through the handling of contaminated clothes or home items handled by an asbestos-exposed person within their household. It is possible to be diagnosed with mesothelioma after breathing asbestos fibers in the clothing of a family member. Research has shown that these types of mesothelioma cases tend to have longer periods of latency and are more likely to be diagnosed in wives than husbands. Scientists are currently studying the possibility that mesothelioma's genetic susceptibility could play a role in the development of the disease. Recent studies have shown the mutation of the gene BAP1 increases the risk of mesothelioma in asbestos-exposed patients. This is particularly important because it could result in improved screening methods for those who are at risk of developing mesothelioma. Researchers have identified a number of genes that are associated with mesothelioma. Some of these genes are involved in reducing the growth of tumors and are frequently altered or mutated in mesothelioma sufferers. These genes include the large homolog 2 of tumor suppressor (LATS2) and NF2. A family history of the disease increases the risk. This is due to certain genes, including BAP1 BAP1 gene, can be passed down from an individual parent. Veterans have the highest rates of mesothelioma compared to other occupational groups because asbestos was heavily used in the military. People who were in the Navy and on ships were at risk the most because of the extensive exposure to asbestos in fireproofing, insulation materials, and shipbuilding.